Step-by-Step Search Guide

• Step 4: Review information gathered in first phase

To evaluate the usefulness of the first phase of the search, review the relevant literature in full rather than just abstracts. This is recommended because often the information relating to Three Rs alternatives is found in the methods section of articles, not abstracts. To identify knowledge gaps that still need to be filled, it may be useful consider some or all of the Questions to assess whether your Three Rs search is complete.


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