Conventional Test Method:

Lethal challenge test for Rabies Vaccine

Alternative Test Method:

Name & Description:

Single dilution assay

Enables the analyst to determine that the vaccine has a potency significantly higher than the required minimum, but does not give full information on the validity of each individual potency determination.

Validation Status:

No information

Regulatory Status:

EU: Accepted in PhEur

Effect or Potential Effect on Animal Use:

Reduction

References:
  • Council of Europe (CE) (2008) 2.7.6 Assay of Diphtheria vaccine (adsorbed). In: European Pharmacopoeia, 6th ed. Strasbourg, France: CE.
Information Last Reviewed:
May 2012