Phototoxicity

Conventional
test method

Alternative Test Method

Last Reviewed
Name & Description Validation Status Regulatory Status Effect or Potential Effect on Animal Use
In vivo Mammalian Phototoxicity Test

In Vitro 3T3 Neural Red Uptake (NRU) Phototoxocity Test
Description and references

EU: Validated by EU/COLIPA and endorsed as valid by ESAC (1997)

OECD: TG 432 (2004)

EU: Accepted by European Commission as method B.41 in Annex V of EU Council Directive 67/548/EEC. This test must be used to determine phototoxic effects of chemicals, and animal tests are prohibited for this purpose in all EU member states (2000)

Replacement May 2012

 

List of Abbreviations

Test Methods Categories

Toxicity
Dermal Tests
Vaccines