Hematotoxicity

Conventional
test method

Alternative Test Method

Last Reviewed
Name & Description Validation Status Regulatory Status Effect or Potential Effect on Animal Use
Haematotoxicity test for acute neutropenia
(use of a second species)
Colony Forming Unit-Granulocyte/Macrophage (CFU-GM) Assay
Description and references
EU: Validated by ECVAM (2006) No information Reduction
(For use in place of a second species in the haematotoxicity test for acute neutropenia;, not a replacement as it relies on the availability of mouse Maximum Tolerated Dose data)
May 2012

 

List of Abbreviations

Test Methods Categories

Toxicity
Dermal Tests
Vaccines