Three Rs Microsite

Your link to information on replacement,
reduction and refinement alternatives
for animal use in science

Three Rs The Three Rs

Replacing animals in science.

Reducing the number of animals used

Refining care and procedures to minimize pain and distress

Learn more
Upcoming EventsUpcoming Events
FRAME Training School in Experimental Design and Statistics of Biomedical Experiments

Voss, Norway
February 1-3, 2016

Symposium on Social Housing of Laboratory Animals

UC Davis School of Veterinary Medicine
Davis, CA
March 17-18, 2016

Pan-American Conference for Alternative Methods

Baltimore, MD
April 12-14, 2016

CALAS 55th Annual Symposium

Toronto, ON
June 11-14, 2016

10th World Congress on Alternatives and Animal Use in the Life Science

The 3Rs in Action
Seattle, WA
September 2017

News & Publications

February 1, 2016

Registration Open for Symposium on Social Housing of Laboratory Animals

Co-hosted by USDA, OLAW, UC Davis School of Veterinary Medicine, Division of Veterinary Resources NIH, and the Johns Hopkins Center for Alternatives to Animal Testing at UC Davis School of Veterinary Medicine Valley Hall Davis, California on March 17-18, 2016.

Registration includes an optional Primate facility tour on March 16th. Attendee registration closes February 29, 2016.

For further information, please contact Jamie DeRita.

January 18, 2016

Comfortable Quarters -- Obtain a free copy of Animal Welfare Institute’s Guide for laboratory animal care personnel on the humane housing and handling of individual animal species in research facilities; edited by Cathy Liss, Kenneth Litwak, Dave Tilford & Viktor Reinhardt; 2015; 10th edition; 239 pages.

January 11, 2016

Winners of the 2015 Dorothy Hegarty Award (for the best publication in the journal ATLA) are from Montréal.

Read the winning paper.
Guo T., Lok K-Y., Yu C. & Li Z. (2014) Lung fibrosis: Drug screening and disease marker identification with lung slice culture model and subtracted cDNA library ATLA 42: 235-243.

Recent publications:

News Archive
Three Rs Searches Three Rs

Three Rs Search Guide
Step-by-step strategy for Three Rs information searches

Animal Use Protocol Worksheet
Tool to organize Three Rs information for protocols

CCAC Reference Database
Database of scientific literature used in CCAC publications

Systematic Review
A method of synthesizing scientific evidence

Animal Index
Three Rs information organized by species

Testing Testing

Alternative Test Methods Table
Validated alternatives to conventional regulatory test methods