Three Rs Microsite

Your link to information on replacement,
reduction and refinement alternatives
for animal use in science

Three Rs The Three Rs

Replacing animals in science.

Reducing the number of animals used

Refining care and procedures to minimize pain and distress

Learn more
Upcoming EventsUpcoming Events
CCAC National Workshop 2015

May 30, 2015
Montréal, QC

CALAS 54th Annual Symposium

One World One Vision
May 30 - June 2, 2015
Montréal, QC

News & Publications

April 27, 2015

The NC3Rs 2014 Annual report is now available.

April 13, 2015

Funding opportunity: The Animal Research & Development Fund (ARDF) 2015 Alternatives Research Grant Program deadline is April 30, 2015.

April 7, 2015

Read this overview of the NC3Rs publication bias workshop held in February 2015.

March 30, 2015

The RSPCA has now published a resource book for lay members of ethical review and similar bodies worldwide.

March 16, 2015

An International Alliance for Biological Standardization (IABS) conference '3Rs Alternatives and Consistency Approach in Vaccine Lot Release Testing' will be held in the Netherlands, September 16 – 18, 2015. Further details can be found on the IABS website.

Recent publications:

News Archive
Three Rs Searches Three Rs

Three Rs Search Guide
Step-by-step strategy for Three Rs information searches

Animal Use Protocol Worksheet
Tool to organize Three Rs information for protocols

CCAC Reference Database
Database of scientific literature used in CCAC publications

Systematic Review
A method of synthesizing scientific evidence

Animal Index
Three Rs information organized by species

Testing Testing

Alternative Test Methods Table
Validated alternatives to conventional regulatory test methods