Three Rs Microsite

Your link to information on replacement,
reduction and refinement alternatives
for animal use in science

Three Rs The Three Rs

Replacing animals in science.

Reducing the number of animals used

Refining care and procedures to minimize pain and distress

Learn more
Upcoming EventsUpcoming Events
FRAME Training School in Experimental Design and Statistics of Biomedical Experiments

Voss, Norway
February 1-3, 2016

Pan-American Conference for Alternative Methods

Baltimore, MD
April 12-14, 2016

CALAS 55th Annual Symposium

Toronto, ON
June 11-14, 2016

10th World Congress on Alternatives and Animal Use in the Life Science

The 3Rs in Action
Seattle, WA
September 2017

Three Rs Searches Three Rs

Three Rs Search Guide
Step-by-step strategy for Three Rs information searches

Animal Use Protocol Worksheet
Tool to organize Three Rs information for protocols

CCAC Reference Database
Database of scientific literature used in CCAC publications

Systematic Review
A method of synthesizing scientific evidence

Animal Index
Three Rs information organized by species

Testing Testing

Alternative Test Methods Table
Validated alternatives to conventional regulatory test methods