Three Rs Microsite

Your link to information on replacement,
reduction and refinement alternatives
for animal use in science


Three Rs The Three Rs

Replacing animals in science.

Reducing the number of animals used

Refining care and procedures to minimize pain and distress

Learn more
Upcoming EventsUpcoming Events
Newcastle Consensus Meeting 2013 - Laboratory animal euthanasia

August 9, 2013
Newcastle upon Tyne, UK


9th World Congress on Alternatives and Animal Use in the Life Sciences

Humane Science in the 21st Century
August 24-28, 2014
Prague, Czech Republic

News & Publications

June 18, 2013

Replacement of animal testing: EURL ECVAM releases its strategy for skin sensitisation hazard identification and classification.


June 5, 2013

Funding Opportunity: Call for Proposals for 2014 CAAT Science-Based Refinement Awards.


May 22, 2013

Read about the Human Toxome Project which aims to map pathways of endocrine disruption, as a first step in mapping the human toxome.


Recent publications:


News Archive
Three Rs Searches Three Rs
 Searches

Three Rs Search Guide
Step-by-step strategy for Three Rs information searches

Animal Use Protocol Worksheet
Tool to organize Three Rs information for protocols

CCAC Reference Database
Database of scientific literature used in CCAC publications

Systematic Review
A method of synthesizing scientific evidence

Animal Index
Three Rs information organized by species

Testing Testing

Alternative Test Methods Table
Validated alternatives to conventional regulatory test methods