Three Rs Microsite

Your link to information on replacement,
reduction and refinement alternatives
for animal use in science


Three Rs The Three Rs

Replacing animals in science.

Reducing the number of animals used

Refining care and procedures to minimize pain and distress

Learn more
Upcoming EventsUpcoming Events
FRAME Training School in Experimental Design and Statistical Analysis of Biomedical Experiments

30 March – 1 April 2015
Coimbra, Portugal


CALAS 54th Annual Symposium

One World One Vision
May 30 - June 2, 2015
Montréal, QC

News & Publications

March 16, 2015

An International Alliance for Biological Standardization (IABS) conference '3Rs Alternatives and Consistency Approach in Vaccine Lot Release Testing' will be held in the Netherlands, September 16 – 18, 2015. Further details can be found on the IABS website.


March 9, 2015

Funding opportunity: The International Foundation for Ethical Research (IFER) Graduate Fellowship Program for Alternatives to the Use of Animals in Science pre-proposal deadline is April 20, 2015.


March 5, 2015

Funding opportunity: The Animal Research & Development Fund (ARDF) 2015 Alternatives Research Grant Program deadline is April 30, 2015.


March 3, 2015

CALAS/ACSAL Awards Program 2015 application deadline is March 20, 2015


New laboratory animal anesthesia e-learning resource from Newcastle University.


Recent publications:


News Archive
Three Rs Searches Three Rs
 Searches

Three Rs Search Guide
Step-by-step strategy for Three Rs information searches

Animal Use Protocol Worksheet
Tool to organize Three Rs information for protocols

CCAC Reference Database
Database of scientific literature used in CCAC publications

Systematic Review
A method of synthesizing scientific evidence

Animal Index
Three Rs information organized by species

Testing Testing

Alternative Test Methods Table
Validated alternatives to conventional regulatory test methods