Three Rs Microsite

Your link to information on replacement,
reduction and refinement alternatives
for animal use in science

Three Rs The Three Rs

Replacing animals in science.

Reducing the number of animals used

Refining care and procedures to minimize pain and distress

Learn more
Upcoming EventsUpcoming Events
American Association for Laboratory Animal Science (AALAS)

65th National Meeting
October 19-23, 2014
San Antonio, TX

OpenTox USA 2015

Driving the Big Science Challenge in Safety Forward
February 11-12, 2015
Baltimore, MD

News & Publications

September 22, 2014

Call for proposals for CAAT 2015 Science-based Refinement Awards — Deadline is October 17, 2014.

For other Three Rs research funding opportunities see the Three Rs Microsite Funding page.

September 15, 2014

The American Association of Laboratory Animal Scientists National Meeting scientific program includes many sessions related to refinement of animal care.

Refinement information can also be found in the Care & Techniques and Animal Index sections of the Three Rs microsite.

September 11, 2014

Read about how one animal-based science company works to create a culture of care.

August 25, 2014

The Society of Toxicology (SOT) Awards deadline is October 9, 2014.

Visit the Three Rs Microsite Funding page to view more details on this and other Three Rs research funding opportunities.

Recent publications:

News Archive
Three Rs Searches Three Rs

Three Rs Search Guide
Step-by-step strategy for Three Rs information searches

Animal Use Protocol Worksheet
Tool to organize Three Rs information for protocols

CCAC Reference Database
Database of scientific literature used in CCAC publications

Systematic Review
A method of synthesizing scientific evidence

Animal Index
Three Rs information organized by species

Testing Testing

Alternative Test Methods Table
Validated alternatives to conventional regulatory test methods