Three Rs Microsite

Your link to information on replacement,
reduction and refinement alternatives
for animal use in science


Three Rs The Three Rs

Replacing animals in science.

Reducing the number of animals used

Refining care and procedures to minimize pain and distress

Learn more
Upcoming EventsUpcoming Events

UFAW 2017 International Symposium. ‘Measuring animal welfare and applying scientific advances – Why is it still so difficult?’

Surrey, UK
June 27-29, 2017


10th World Congress on Alternatives and Animal Use in the Life Science

The 3Rs in Action
Seattle, WA
August 20-24, 2017

News & Publications

March 22, 2017

CAAT call for pre-proposals

The Center for Alternatives to Animal Testing (CAAT) research grants program at the Johns Hopkins’ Bloomberg School of Public Health has put out a call for pre-proposals for the 2018-19 program, with a deadline of April 21, 2017. Visit the CATT research grants program website for complete information and to complete the pre-proposal form.


December 19, 2016

Score Sheets and Postoperative Analgesia

This month’s edition of Laboratory Animals (Volume 50, Issue 6, December 2016) features a special edition: Score Sheets and Postoperative Analgesia, with guest editors Huw Golledge and Paula Jirkoff.


November 16, 2016

Animal Models for Microbiome Research: Advancing Basic and Translational Science

Join the ILAR Roundtable for a free two-day workshop on December 19-20, 2016 to examine animal models of microbiome research. Invited speakers will discuss challenges of standardization and biological variability in using gnotobiotic model organisms, examine the translatability of preclinical studies to humans, identify alternative model organisms that can be used in microbiome research, and discuss strategies for expanding the infrastructure and tools for conducting studies in these types of models. Click here to view the final agenda, including speakers and topics. This workshop will be held at 500 5th Street NW, Washington, DC and will be freely available via webcast. We invite you to join us in person or via webcast.

Please register to attend today!


Recent publications:


News Archive
Three Rs Searches Three Rs
 Searches

Three Rs Search Guide
Step-by-step strategy for Three Rs information searches

Animal Use Protocol Worksheet
Tool to organize Three Rs information for protocols

CCAC Reference Database
Database of scientific literature used in CCAC publications

Systematic Review
A method of synthesizing scientific evidence

Animal Index
Three Rs information organized by species

Testing Testing

Alternative Test Methods Table
Validated alternatives to conventional regulatory test methods